amyloid-β相关论文
Amyloid cross-seeding between Aβ and hIAPP in relation to the pathogenesis of Alzheimer and type 2 d
Amyloid cross-seeding of different amyloid proteins is considered as a highly possible mechanism for exacerbating the tr......
目的探讨叶酸缺乏对APP/PS1双转基因阿尔茨海默病（Alzheimer’s disease, AD）模型小鼠脑组织中早老素1(Presenilin1)基因表达和β-淀......
To enhance anti-amyloid-beta(Aβ) antibody generation and induce a Th2 immune response,we constructed a new DNA vaccine ......
目的:制备靶向β-淀粉样蛋白(Aβ)的单链抗体(scFv),探究其体外活性。方法:原核表达系统对scFv进行表达。ELISA、免疫组化法检测sc......
目的观察β-淀粉样蛋白（Aβ）_（25-35）对大鼠海马Caspase-3及P38MAPK mRNA表达的影响。方法雄性Sprague-Dawley（SD）大鼠24只,随机分为正常......
用常规的T2加权像研究阿尔茨海默病双转基因APPswe/PS1dE9小鼠模型,拟合了海马和顶叶皮层的T2,并用组织学方法研究了APP/PS1小鼠在......
β-淀粉样多肽（β-amyloid peptide,Aβ）在细胞膜上的错误折叠和聚集与阿尔茨海默病的发病机理有关,研究Aβ和细胞膜之间的相互作用......
Alzheimer’s disease (AD) is the most common form of dementia which mostly affects persons younger than 65 years old. Mo......
目的：探讨Aβ25-35介导SH-SY5Y细胞Bcl-2、Bax基因表达改变是否通过基因启动子区甲基化的机制。方法不同浓度Aβ25-35（0、25、50μmo......
